\[4x^{2}y^{5} = 3 \Longrightarrow \ \ x^{2}y^{5} = \frac{3}{4}:\]
\[- 20x^{4}y^{10} = - 20\left( x^{2}y^{5} \right)^{2} =\]
\[= \frac{- 20 \cdot 9}{16} = - \frac{45}{4} = - 11\frac{1}{4}.\]