\[\frac{2x - 1}{4} - \frac{x + 3}{8} < - 4\ \ \ | \cdot 8\]
\[4x - 2 - x - 3 < - 32\]
\[3x < - 27\]
\[x < - 9\]
\[Ответ:( - \infty;\ - 9).\]