\[\frac{4\sin\alpha - 3\cos\alpha}{2\sin\alpha + 5\cos\alpha} =\]
\[= \frac{4\frac{\sin\alpha}{\cos\alpha} - \frac{3\cos\alpha}{\cos\alpha}}{2\frac{\sin\alpha}{\cos\alpha} + 5\frac{\cos\alpha}{\cos\alpha}} =\]
\[= \frac{4tg\ \alpha - 3}{2tg\ \alpha + 5} = \frac{4 \cdot ( - 3) - 3}{2 \cdot ( - 3) + 5} =\]
\[= \frac{- 12 - 3}{- 6 + 5} = \frac{- 15}{- 1} = 15.\]