\[- 12x^{3}y^{9}z^{10} \cdot 1\frac{5}{6}x^{7}y =\]
\[= - 12 \cdot \frac{11}{6}x^{10}y^{10}z^{10} =\]
\[= - 22x^{10}y^{10}z^{10}\]